DNA Fingerprinting

eQMS::DNA

DNA Typing
DNA Testing
DNA Profiling
DNA Fingerprinting
Forensic DNA Database


DNA Typing

eQMS::DNA is a software for maintenance and efficient searching of database of human genotypes for forensic purposes - also known as DNA Fingerprinting, DNA Profiling, DNA Typing or DNA Testing Software.

eQMS::DNA maintains database of DNA profiles of convicted offenders, unsolved crime scene evidence but of missing persons also. eQMS::DNA enables law enforcement authorities to quickly and reliably compare DNA profiles collected on a crime scene with one stored in eQMS::DNA database and identify potential offenders.

Pardus' DNA database software maintains data on individual donors with optional personal and demographic data, multiple samples containing genetic material taken from the donor, and genotypes obtained from the samples, possibly using multiple techniques and identification kits. Both processed genotypes and optional additional data such as peak quality and confidence parameters and raw electroferograms can be kept. The system also keeps profiles of as yet unidentified traces.

The CSI DNA database can contains not only full DNA profiles (e.g. 13-loci CODIS standard), but also partial ones obtained using different identification kits. While searching it is possible to relax match criteria -- e.g. specify one base pair identification error tolerance.

The searches can be performed interactively or in fully automatic mode. Pardus' DNA profiling system also supports mixed-stain searches with provisions for common contaminant identification -- such as genotypes of laboratory or other forensic personnel.

The CSI DNA fingerprinting system computes probability of random match using either population statistics gathered from profiles already in the database, or known allele distribution data for a particular population. Arbitrary number of distribution sets can be kept (including historical distributions from the database, necessary for retests).

The type of polymorphisms and number of loci used for constructing genotypes is configurable, but typical installation will employ a standard set of 13 to 18 STR loci. Manual entry of data from plate gel electrophoresis is also possible, but typical data source will be results from automated capillary electrophoresis sequencers.

Apart from human forensic applications eQMS::DNA can be also successfully applied as a reliable and efficient tool for implementation of meat traceability. eQMS::DNA enables tracing of animal food products through the supply chain back to source animals, offering unprecedented levels of traceability.

eQMS::DNA employs role-based access control with fine granularity (up to the attribute level). Full audit trail log is kept. The system fully adheres to CFR 21 part 11 recommendations. eQMS::DNA can be deployed either as a stand alone system or can be integrated with LIMS or forensic case management system such as Pardus' forensic LIMS eQMS::LIMS.

Vidi e-novation 2007 evaluation committee awarded Pardus in category "Enterprises Acknowledgements" with two special acknowledgements for Pardus' eQMS::LIMS (cross industry laboratory information management system - LIMS) and eQMS::DNA (forensic DNA typing and maintenance system).

Apart from human forensic applications eQMS::DNA can be also successfully applied as a reliable and efficient tool for implementation of meat traceability. eQMS::DNA enables tracing of animal food products through the supply chain back to source animals.